Pharmacological activity is associated with the presence of polysaccharides in the composition of shiitake, the leading of which is lentinan, which belongs to the group of biological response modifiers. Lentinan, used in relatively small doses, exhibits great antitumor activity. It stimulates the activity of the immune system, which plays a major role in the destruction of tumors. Lentinan enhances various immune functions of the body, and does not attack the tumor cells or viruses themselves, increasing the phagocytic activity of macrophages.Other polysaccharides that make up shiitake have a similar effect: emitanin and KS-2.
Shiitake polysaccharides act by normalizing immune processes by stimulating natural killer cells (NK cells) and killer T lymphocytes. Amino acids, including essential ones (leucine, isoleucine, lysine, threonine, methionine, phenylalanine, tryptophan, valine), B vitamins (thiamine, riboflavin, niacin) and D vitamins restore the blood formula. Vitamin D3 (calciferol) is involved in the regulation of immunogenesis and cell proliferation and potentiates the effect of the cytostatic agent on the tumor.
In addition, shiitake contains phytonutrients - "virus-like particles", which cause the body itself to produce interferon - a powerful protein component of the immune system that blocks the multiplication of viruses.
Shiitake is highly effective for hepatitis, herpes, flu and other viral diseases.
β-glucans, L-ergothioneine, triterpenes, polyunsaturated fatty acids, alkaloids, glycosides, polysaccharides (mainly from b-1-3 and b-1-6 glucans), NK cells, T cells, reactive nitrogen species, O2, intermediates, interleukins, G. lucidum triterpenoids (including the C30-hydrocarbon skeleton), vitamins, microelements
Functions
Ganoderma lucidum (Reishi, lacquered tinder fungus, 'mushroom of immortality') is a traditional remedy used in Chinese and Japanese medicine for two millennia. In traditional Chinese medicine, Ganoderma is assigned the highest category in terms of its breadth of action and lack of side effects.
Based on research conducted at the Tokyo Institute of Carcinogenesis, the Japanese government has officially listed the dry extract of the fruit fungus Ganoderma on the list of medicinal anticancer drugs.
Ganoderma contains a large number of unique biologically active molecules such as polysaccharides and triterpenoids. Triterpenoids have antihypertensive, hypocholesterolemic, hepatoprotective, antihistamine, antitumor and antiangiogenic effects. Ganoderma polysaccharides have an antitumor effect. In addition, they have a shielding effect against free radicals and reduce the damage caused by mutagens.
Terpenoids increase resistance to stress, which is the main definition for adaptogens.
The anti-aging effect of ganoderma mycelium extract is manifested in the stimulation of neuronal differentiation. Removal of nerve growth factor (NGF) during cell culture induces apoptosis, and administration of mycelium extract can induce cell differentiation and prevent apoptosis.
The main components of chaga (β-glucans and a chromogenic complex) exhibit many biological activities, including antitumor, antioxidant, hypoglycemic and immunostimulating effects. The cytoprotective effects of chaga against apoptosis (caused by oxidative stress) and premature aging have also been proven.
β-glucans, laccases, trace elements (selenium, iron, proteins, potassium, calcium, magnesium, phosphorus, zinc), vitamins B, C
Functions
Contains a group of strong antioxidants, is a pronounced adaptogen and antibacterial agent. Antimicrobial analysis in vitro showed that mycelium extract has high antibacterial activity against bacteria E. coli, Bacillus subtilis, B. licheniformis, S. aureus. Lentinus tigrinus is a natural source of safe anti-diabetic food supplements. The action of the fungus is comparable to the results of the antidiabetic agent glibenclamide, which was used as a positive control
Probiotics, gluconic and lactic acids, polyphenols, B vitamins, vitamin C, zinc, calcium, magnesium, iron, copper
Functions
The greatest benefit of kombucha is its probiotic "character": it restores the intestinal flora after antibiotic treatment and effectively strengthens the immune system. Kombucha significantly improves digestion, stimulates metabolism and accelerates fat burning, has high detoxification characteristics and is effectively used to cleanse the blood. Possesses hepatoprotective and nephroprotective properties: it has a positive effect in chronic diseases of the liver and kidneys, and also protects these organs under adverse conditions.
Effects
· Saturation of the body with probiotics
· Restoration of intestinal microflora
· Improving digestion
· Restoration of metabolism
· Acceleration of fat burning
· Antioxidant activity
· Hepatoprotector
The biologically active components in Hericium coralloides known as herikenones and erinacins stimulate the production of nerve growth factor in nerve cells, stimulating the growth of nerve and brain cells, thereby helping to maintain the function of the forebrain. Erinacin E, isolated from the Hericium coralloides, is one of the most powerful stimulants of nerve cell growth, and therefore has become a potential drug against Alzheimer's disease.
The mushroom is on the verge of extinction, therefore, in natural conditions, it practically cannot be found.
Effects
· Maintenance and regeneration of certain populations of neurons in the brain
· Increased neurotrophic activity
· Antioxidant activity
· Antitumor activity
· Immunomodulation
Is one of the most popular medicinal and edible mushrooms producing secondary metabolites with potential to treat neurodegenerative diseases.
This activity is attributed to the discovery of various terpenoids that can stimulate the production of nerve growth factor (NGF) or brain neurotrophic factor (BDNF) in cellular bioassays, which may help in Parkinson's, Alzheimer's and Huntington's diseases, which are accompanied by a decrease in the expression of neurotrophic factor.
The fungus has a beneficial effect on the gastrointestinal tract, it is used in the treatment of atrophic gastritis. Provides a source of vitamin B12.
Effects
· Neuroprotective action
· Maintaining and regenerating specific populations of neurons in the brain
· Antioxidant activity
· Antitumor activity
· Immunomodulation
